Our mission is to improve the lives of patients with diabetes. As a lab, we are working to discover the pathways and metabolites that underlie the development of diabetes-associated diseases, like atherosclerosis. We are fascinated by metabolism, and curious about the many metabolic derangements caused by diabetes. We strive to think creatively and critically, ask important questions, and uphold the highest experimental standards. Though creating new technologies is not our primary goal, we use whatever approaches are necessary to answer our questions--integrating biochemical, molecular, cellular, proteomic and mouse genetic approaches with clinical studies in humans. We expect that our work will ultimately enable the development of better therapies for our obese and diabetic patients.